BDBM50547333 CHEMBL3742191

SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(c2)[N+]([O-])=O)c2ccccc12

InChI Key InChIKey=RSLYIDUWLDFWGF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547333   

TargetTumor necrosis factor ligand superfamily member 11(Human)
Agricultural University of Athens

Curated by ChEMBL
LigandPNGBDBM50547333(CHEMBL3742191)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Human)
Agricultural University of Athens

Curated by ChEMBL
LigandPNGBDBM50547333(CHEMBL3742191)
Affinity DataKd:  2.18E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed