BDBM50547326 CHEMBL4779613

SMILES COc1c(F)ccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N

InChI Key InChIKey=AXRXVDQBZDUWIW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547326   

TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50547326(CHEMBL4779613)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50547326(CHEMBL4779613)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed