BDBM50547282 CHEMBL4765124

SMILES OC(=O)[C@@H]1CCCCN1Cc1ccc(OCc2cccc(c2Br)-c2ccccc2)cc1

InChI Key InChIKey=ACKVFEIIXDXISB-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547282   

TargetProgrammed cell death 1 ligand 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547282(CHEMBL4765124)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to human PD1-L1 (18-134 residues) expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by MST analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547282(CHEMBL4765124)
Affinity DataEC50:  6.60E+3nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed