BDBM50547225 CHEMBL4757990

SMILES COC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@H](N1C(=O)CCl)c1ccc(cc1)C(=O)OC

InChI Key InChIKey=TXJZRSRTYPUYRW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547225   

TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50547225(CHEMBL4757990)
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50547225(CHEMBL4757990)
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed