BDBM50547126 CHEMBL4763473

SMILES FC(F)(F)c1cccc(Nc2ccccc2C(=O)CCl)c1

InChI Key InChIKey=JPVDFGYNLUBCSD-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50547126   

TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547126(CHEMBL4763473)
Affinity DataIC50: 800nMAssay Description:Inhibition of CPM binding to N-terminal His6-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cells p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547126(CHEMBL4763473)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of FITC-labeled palmitate tracer binding to N-terminal His6-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21-Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50547126(CHEMBL4763473)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of FAM-labelled GST-tagged full-length YAP (60 to 99 residues)(unknown origin)/GST-tagged TEAD4 (217 to 434 residues) (unknown origin) exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50547126(CHEMBL4763473)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of FAM-labelled GST-tagged full-length YAP (60 to 99 residues)(unknown origin)/N-terminal His-tagged TEAD2(217 to 447 residues) (unknown o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547126(CHEMBL4763473)
Affinity DataEC50:  5.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547126(CHEMBL4763473)
Affinity DataKi:  1.04E+4nMAssay Description:Inhibition of CPM binding to N-terminal His6-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cells p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed