BDBM50546611 CHEMBL4762472

SMILES CN(C)c1cc(cc(n1)-c1ccc(cc1)C(O)=O)C(=O)N1CCC2(CC1)CC(=O)c1nn(cc1O2)C(C)(C)C

InChI Key InChIKey=KFLUNUSHNNCWKD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50546611   

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546611(CHEMBL4762472)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546611(CHEMBL4762472)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546611(CHEMBL4762472)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546611(CHEMBL4762472)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed