BDBM50546610 CHEMBL4799861

SMILES CC(C)(C)n1cc2OC3(CCN(CC3)C(=O)c3ccnc(c3)-c3ccc(cc3)C(O)=O)CC(=O)c2n1

InChI Key InChIKey=FIAQCQHMUMHZHV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50546610   

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546610(CHEMBL4799861)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546610(CHEMBL4799861)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546610(CHEMBL4799861)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546610(CHEMBL4799861)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed