BDBM50546545 CHEMBL4753754

SMILES COc1cc(ccc1-c1cn[nH]c1)C(=O)N[C@H](C)c1ccccc1F

InChI Key InChIKey=WHGWETKOANDIKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546545   

TargetRho-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50546545(CHEMBL4753754)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ROCK1 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH peptide substrate by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50546545(CHEMBL4753754)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH peptide substrate by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed