BDBM50546473 CHEMBL4759472

SMILES CCN1CCC2(C[C@@H]2C(=O)N[C@@H](CCCCCC(=O)CC)c2[nH]c(nc2C#N)-c2ccc(F)cc2)CC1

InChI Key InChIKey=BCFDVKOJXXCTFO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546473   

TargetHistone deacetylase 1/2/3/8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50546473(CHEMBL4759472)
Affinity DataEC50:  259nMAssay Description:Inhibition of Class 1 HDAC in VSV-G-pseudotyped HIV infected human 2C4 cell Jurkat model assessed as reactivation of HIV latency in presence of 5% NH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50546473(CHEMBL4759472)
Affinity DataEC50:  161nMAssay Description:Inhibition of Class 1 HDAC in VSV-G-pseudotyped HIV infected human 2C4 cell Jurkat model assessed as reactivation of HIV latency in presence of 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed