BDBM50546465 CHEMBL4761973

SMILES CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC11CCN(C)CC1)c1[nH]c(nc1C#N)-c1ccc2nn(C)cc2c1

InChI Key InChIKey=CSAXKBIVUGNWAI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546465   

TargetHistone deacetylase 1/2/3/8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50546465(CHEMBL4761973)
Affinity DataEC50:  322nMAssay Description:Inhibition of Class 1 HDAC in VSV-G-pseudotyped HIV infected human 2C4 cell Jurkat model assessed as reactivation of HIV latency in presence of 5% NH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50546465(CHEMBL4761973)
Affinity DataEC50:  247nMAssay Description:Inhibition of Class 1 HDAC in VSV-G-pseudotyped HIV infected human 2C4 cell Jurkat model assessed as reactivation of HIV latency in presence of 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed