BDBM50546392 CHEMBL4750845

SMILES CCOC(=O)c1cc2c(s1)c1ccc(O)cc1oc2=O

InChI Key InChIKey=ZLRYSLHVRPSJMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50546392   

LigandPNGBDBM50546392(CHEMBL4750845)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of JAK in human PBMC assessed as inhibition of IL2-induced STAT5 phosphorylation preincubated for 30 mins followed by addition IL2 stimula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50546392(CHEMBL4750845)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of JAK in human PBMC assessed as inhibition of GM-CSF-induced STAT5 phosphorylation preincubated for 30 mins followed by addition IL2 stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50546392(CHEMBL4750845)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of JAK in human PBMC assessed as inhibition of IFNalpha-induced STAT1 phosphorylation preincubated for 30 mins followed by addition IL2 st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed