BDBM50546279 CHEMBL4742719

SMILES [H][C@@]12C\C(=N\OC(=O)c3ccc(cc3)C(=O)O\N=C3\C[C@@]4([H])C(C)(C)CCC[C@]4(C)C(CCc4ccoc4)=C3C)C(C)=C(CCc3ccoc3)[C@@]1(C)CCCC2(C)C

InChI Key InChIKey=CTMUMEQHSGMHFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50546279   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Universidad Complutense De Madrid (Ucm)

Curated by ChEMBL
LigandPNGBDBM50546279(CHEMBL4742719)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and nigerecin-induced IL-1beta production pre-stimulated with LPS for 5 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed