BDBM50546217 CHEMBL4798989

SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(C)n(-c3ccc(Oc4ccn(C)n4)c(Cl)c3Cl)c(=O)c2C)[C@@H]1N

InChI Key InChIKey=IJMLGRJLGUDSJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50546217   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546217(CHEMBL4798989)
Affinity DataIC50: 3nMAssay Description:Inhibition of human SHP2 E76K mutant expressed in Escherichia coli using DiFMUP as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed