BDBM50546204 CHEMBL4780264

SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(O)=O

InChI Key InChIKey=AJVDIBTZNDJXEE-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50546204   

Target72 kDa type IV collagenase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50546204(CHEMBL4780264)
Affinity DataIC50: 30nMAssay Description:Inhibition of MMP2 (unknown origin) using 3163v as substrate preincubated for 15 mins followed by substrate addition and measured after 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50546204(CHEMBL4780264)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human MT1-MMP using 3163v as substrate preincubated for 15 mins followed by substrate addition and measured after 40 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50546204(CHEMBL4780264)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin) using 3168v as substrate preincubated for 15 mins followed by substrate addition and measured after 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetMatrilysin(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50546204(CHEMBL4780264)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP7 using 3163v as substrate preincubated for 15 mins followed by substrate addition and measured after 40 mins by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50546204(CHEMBL4780264)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP9 using 3163v as substrate preincubated for 15 mins followed by substrate addition and measured after 40 mins by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50546204(CHEMBL4780264)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 10 to 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50546204(CHEMBL4780264)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 10 to 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed