BDBM50546202 CHEMBL3892335

SMILES [H][C@]1(O)CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@]1([H])c1cc(F)ccc1F

InChI Key InChIKey=NYNZQNWKBKUAII-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50546202   

TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50546202(CHEMBL3892335)
Affinity DataIC50: 46nMAssay Description:Inhibition of N-terminal His6-tagged TRKA G667C mutant (unknown origin) (486 to 786 residues) expressed in Escherichia coli using poly-EAY substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50546202(CHEMBL3892335)
Affinity DataIC50: 69nMAssay Description:Inhibition of N-terminal His6-tagged TRKA G595R mutant (unknown origin) (486 to 786 residues) expressed in Escherichia coli using poly-EAY substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50546202(CHEMBL3892335)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal His6-tagged TRKA (unknown origin) (486 to 786 residues) expressed in Escherichia coli using poly-EAY substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed