BDBM50546129 CHEMBL4785324

SMILES N[C@H]([C@@H](O)CN(C1CCC1)S(=O)(=O)c1ccc2scnc2c1)c1ccccc1

InChI Key InChIKey=RCSDMZMTLQPVDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546129   

TargetSignal peptide peptidase-like 2A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50546129(CHEMBL4785324)
Affinity DataIC50: 840nMAssay Description:Inhibition of human SPPL2a expressed in HEK293 cells cotransfected with Gal4 luciferase reporter plasmid and VP16-TNFalpha(1-76)-NTF incubated for 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50546129(CHEMBL4785324)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in HEK293 cells cotransfected with Notch1-VP16-GAL4 fusion and Gal4 luciferase reporter plas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed