BDBM50546117 CHEMBL4763626

SMILES NCCO\N=C1\C(\Nc2ccc(O)cc\12)=C1\C(=O)Nc2ccc(cc12)[N+]([O-])=O

InChI Key InChIKey=XPFFDDFVHAFKNR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50546117   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50546117(CHEMBL4763626)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50546117(CHEMBL4763626)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of GSK3beta (unknown origin) using PASVPPSPSLSRHSSPHQpSED as substrate preincubated for 10 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50546117(CHEMBL4763626)
Affinity DataIC50: 222nMAssay Description:Inhibition of recombinant human N-terminal His-tagged Aurora A expressed in Sf21 cells using peptide substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50546117(CHEMBL4763626)
Affinity DataIC50: 222nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50546117(CHEMBL4763626)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed