BDBM50546057 CHEMBL4781873

SMILES CC(C)Cc1nnc(o1)N1CC(C1)NC(=O)c1sc2nnc(Cl)c(C)c2c1N

InChI Key InChIKey=UYWTUNWPZXNWKD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546057   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50546057(CHEMBL4781873)
Affinity DataEC50:  230nMAssay Description:Positive allosteric modulation of human M4 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50546057(CHEMBL4781873)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M2 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed