BDBM50545723 CHEMBL4637451

SMILES CC\C(=C/c1ccccc1)[C@@H]1C[C@H]1NC1CC2(C1)CN(C2)C1COC1

InChI Key InChIKey=QKLROSRUQBSAMC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545723   

TargetLysine-specific histone demethylase 1A(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50545723(CHEMBL4637451)
Affinity DataEC50:  4nMAssay Description:Inhibition of LSD1 in human MV4-11 cells assessed as induction of LY96 mRNA expression incubated for 16 hrs by chemiluminescent methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50545723(CHEMBL4637451)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal His-tagged LSD1 (unknown origin) expressed in Escherichia coli expression system using ART-K(Me1)-QTARKSTGGKAPRK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed