BDBM50545630 CHEMBL4639676

SMILES CC1CCN(C1)c1nc(Nc2ccc(cc2)C(N)=O)ncc1C(F)(F)F

InChI Key InChIKey=CNMSKBUBZCUNLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545630   

TargetTyrosine-protein kinase JAK3(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545630(CHEMBL4639676)
Affinity DataIC50: 61nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545630(CHEMBL4639676)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human Lck using TK-substrate-biotin as substrate incubated for 60 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed