BDBM50545584 CHEMBL4640492::US11530193, Example 4

SMILES CC(C)(C#N)c1cccc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)c1

InChI Key InChIKey=MMOJZTWBARSKGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545584   

TargetCalcium/calmodulin-dependent protein kinase type 1D(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545584(CHEMBL4640492 | US11530193, Example 4)
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant human full-length His-tagged CAMK1D expressed in baculovirus expression system using autocamtide-2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545584(CHEMBL4640492 | US11530193, Example 4)
Affinity DataIC50: 96nMAssay Description:The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
Go to US Patent