BDBM50545382 CHEMBL4646450

SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CCCCNC(=O)CNc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)CC3)nc2n(C2CCCC2)c1=O

InChI Key InChIKey=AWPNCYPNCSCZFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545382   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed