BDBM50545381 CHEMBL4649032

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](C[C@H]1C(=O)Nc1c(F)cccc1F)NC(=O)CCOCCOCCOCCNC(=O)CN1CCN(CC1)c1ccc(Nc2ncc3c(C)c(C(C)=O)c(=O)n(C4CCCC4)c3n2)nc1)C(C)(C)C

InChI Key InChIKey=DNVODRITWXGBQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545381   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed