BDBM50545265 CHEMBL4642268

SMILES CSc1nc2ccccc2n1-c1csc(NC\C(C)=N\N=C2/SCC(=O)N2c2ccccc2)n1

InChI Key InChIKey=LARVQAAGTBVQRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545265   

TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545265(CHEMBL4642268)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545265(CHEMBL4642268)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed