BDBM50545132 CHEMBL4646976

SMILES NS(=O)(=O)NNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=BYFORFAOTUSAIT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545132   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50545132(CHEMBL4646976)
Affinity DataIC50: 218nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 60 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50545132(CHEMBL4646976)
Affinity DataEC50:  101nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed