BDBM50545115 CHEMBL4633986

SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1c(N2CCCCC2)c2ccccc2n(C)c1=O

InChI Key InChIKey=XLZIGNHVEZZVFI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545115   

TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545115(CHEMBL4633986)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545115(CHEMBL4633986)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed