BDBM50545100 CHEMBL1990482

SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1

InChI Key InChIKey=CZIGMBNEFWBEMD-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50545100   

TargetSerine/threonine-protein kinase N2(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50545100(CHEMBL1990482)
Affinity DataIC50: 64nMAssay Description:Displacement of tracer from PKN2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50545100(CHEMBL1990482)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of tracer from PKN1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50545100(CHEMBL1990482)
Affinity DataKi:  30nMAssay Description:Displacement of tracer from PKN2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50545100(CHEMBL1990482)
Affinity DataKi:  40nMAssay Description:Inhibition of His/GST-tagged PKN2 (unknown origin) using biotinylated peptide as substrate measured after 1 hr in presence of [gamma-33P]-ATP by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50545100(CHEMBL1990482)
Affinity DataKi:  540nMAssay Description:Displacement of tracer from PKN1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50545100(CHEMBL1990482)
Affinity DataKi: <1.00E+5nMAssay Description:Inhibition of His/GST-tagged PKN1 (unknown origin) using biotinylated peptide as substrate measured after 1 hr in presence of [gamma-33P]-ATP by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50545100(CHEMBL1990482)
Affinity DataKi: <1.00E+5nMAssay Description:Inhibition of His/GST-tagged CLK4 (unknown origin) using biotinylated peptide as substrate measured after 1 hr in presence of [gamma-33P]-ATP by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed