BDBM50545078 CHEMBL4645055

SMILES [H][C@]1(Cc2ccc(OCCCCCC(=O)N[C@@H](Cc3c[nH]cn3)C(=O)N1)cc2)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

InChI Key InChIKey=CWPWATULNKVZGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545078   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50545078(CHEMBL4645055)
Affinity DataIC50: 646nMAssay Description:Inhibition of His6/GST-tagged human SIRT1 deacetylation activity using SIRT1 acetyl-lysine as substrate in presence of beta-NAD+ after 10 mins by rev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50545078(CHEMBL4645055)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of His6-tagged human SIRT2 deacetylation activity using SIRT1 acetyl-lysine as substrate in presence of beta-NAD+ after 12 mins by reverse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
LigandPNGBDBM50545078(CHEMBL4645055)
Affinity DataIC50: 530nMAssay Description:Inhibition of His6-tagged human SIRT3 deacetylation activity using SIRT3 acetyl-lysine as substrate substrate in presence of beta-NAD+ after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed