BDBM50545029 CHEMBL4642779

SMILES CN(C1CCN(CC1)C(=O)c1ccccc1Nc1ccc(cc1)C(O)=O)C(=O)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=YHHSTWFFSXUGJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545029   

TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545029(CHEMBL4642779)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed