BDBM50545004 CHEMBL4633409

SMILES CCc1nc(N)nc(N)c1-c1ccc(\C=C\C(=O)NO)cc1

InChI Key InChIKey=JOYSLHNWDIQPJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545004   

TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50545004(CHEMBL4633409)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate preincubated for 30 mins followed by substrate addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50545004(CHEMBL4633409)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate 3 preincubated for 30 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50545004(CHEMBL4633409)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate class 2A preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed