BDBM50545001 CHEMBL4649487

SMILES CCc1nc(N)nc(N)c1-c1ccc(cc1)-c1cn(CCCCCC(=O)NO)nn1

InChI Key InChIKey=QCVCOCOMJLADHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545001   

TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50545001(CHEMBL4649487)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate preincubated for 30 mins followed by substrate addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50545001(CHEMBL4649487)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate 3 preincubated for 30 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50545001(CHEMBL4649487)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate class 2A preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed