BDBM50544939 CHEMBL4645000

SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#8]-[#6](-[#6]-[#6]-[#8]-[#6](-[#6])=O)\[#6]=[#6]\[#6]=[#6]\C#CC#C\[#6]=[#6]\[#6]-[#8]

InChI Key InChIKey=QNKKKYRIWOSGLJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50544939   

TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 3.28E+4nMAssay Description:Inhibition of human SOAT1 mediated [14C]Cholesterol ester synthesis in CHO cells after 6 hrs in presence of [14C]Oleic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of human SOAT2-mediated [14C]Cholesterol ester synthesis in CHO cells after 6 hrs in presence of [14C]Oleic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human SOAT1-mediated [14C]Cholesterol ester biosynthesis in CHO microsomal fraction after 5 mins in presence of [1-14C]oleoyl-CoA by TL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human SOAT2-mediated [14C]Cholesterol ester biosynthesis in CHO microsomal fraction after 5 mins in presence of [1-14C]oleoyl-CoA by TL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed