BDBM50544731 CHEMBL4642445

SMILES COC(=O)CN(C)C(=O)C[C@H](CCC1CCCCC1)NC(=O)c1cc(-c2c(OC)cccc2OC)n(CC(C)C)n1

InChI Key InChIKey=HSEBECGWTBSSRH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50544731   

TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50544731(CHEMBL4642445)
Affinity DataEC50:  453nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHOK1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50544731(CHEMBL4642445)
Affinity DataEC50:  1.85E+3nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50544731(CHEMBL4642445)
Affinity DataEC50:  237nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHO cells co-expressing Galphaq16 assessed as increase in intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed