BDBM50544710 CHEMBL4642117

SMILES Oc1ccc(cc1)C(c1ccc(O)cc1)C(Br)(Br)Br

InChI Key InChIKey=CSHGNLUDXTVAEE-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50544710   

TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataEC50:  15nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed