BDBM50544634 CHEMBL4632955

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@](F)(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@]1(O)C#C

InChI Key InChIKey=MXYBEKWDMRRHJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544634   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50544634(CHEMBL4632955)
Affinity DataIC50: 130nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled ribonucleotide monophosphates incorporation into R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed