BDBM50544473 CHEMBL4641073

SMILES COc1ccc2nc(NC(=O)c3ccc(cc3)C(=O)NCc3ccccc3)sc2c1

InChI Key InChIKey=NSBSEDBIIAWIEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544473   

TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544473(CHEMBL4641073)
Affinity DataIC50: 18nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544473(CHEMBL4641073)
Affinity DataIC50: 60nMAssay Description:Inhibition of SCD in human H2009 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed