BDBM50544457 CHEMBL4641007

SMILES COc1ccc2nc(NC(=O)c3ccc(cc3)[C@H](N)c3ccccc3)sc2c1

InChI Key InChIKey=BHOBUXPHKZSABC-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50544457   

TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 180nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs in presence of CYP4F inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of SCD in empty vector transfected human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 27nMAssay Description:Inhibition of SCD in CYP4F11 transfected human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs in presence of oleate by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCD in human H1395 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCD in human HCC366 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCD in human HCC417 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCD in human H1993 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCD in human H2073 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 116nMAssay Description:Inhibition of SCD in human HCC44 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 85nMAssay Description:Inhibition of SCD in human H460 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 50nMAssay Description:Inhibition of SCD in human HCC95 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 11nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCD in human H1819 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544457(CHEMBL4641007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCD in human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed