BDBM50544455 CHEMBL4647386

SMILES N[C@H](c1ccccc1)c1ccc(cc1)C(=O)Nc1nc2ccc(O)cc2s1

InChI Key InChIKey=WMHWSQSRVLCBCN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50544455   

TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544455(CHEMBL4647386)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs in presence of oleate by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544455(CHEMBL4647386)
Affinity DataIC50: 10nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs in presence of CYP4F inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544455(CHEMBL4647386)
Affinity DataIC50: 9nMAssay Description:Inhibition of SCD in empty vector transfected human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544455(CHEMBL4647386)
Affinity DataIC50: 200nMAssay Description:Inhibition of SCD in CYP4F11 transfected human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50544455(CHEMBL4647386)
Affinity DataIC50: 8nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed