BDBM50543919 CHEMBL4645731

SMILES COc1c(ccc(O[C@@H](C)C(F)(F)F)c1C(=O)N1CC(C1)c1ccccc1)S(C)(=O)=O

InChI Key InChIKey=RLLRFBFXJFBMEH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543919   

TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50543919(CHEMBL4645731)
Affinity DataIC50: 96nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50543919(CHEMBL4645731)
Affinity DataIC50: 220nMAssay Description:Inhibition of human GlyT1 expressed in human HEK cells assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50543919(CHEMBL4645731)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology QPatch assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed