BDBM50543781 CHEMBL4632409::US11427591, Compound 1

SMILES Cc1ccc2c(Nc3cccc(c3)C(F)(F)F)noc2c1C#Cc1cnc2cccnn12

InChI Key InChIKey=GDBAAUWGHRTFSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543781   

TargetEpithelial discoidin domain-containing receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50543781(CHEMBL4632409 | US11427591, Compound 1)
Affinity DataIC50: 10nMAssay Description:Inhibition of human DDR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50543781(CHEMBL4632409 | US11427591, Compound 1)
Affinity DataIC50: 9.72nMAssay Description:The activity of the inhibitor compounds against DDR1 and DDR2 was tested using KinaseProfiler (Eurofins). Human DDR1/DDR2 kinase was incubated with 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent