BDBM50543722 CHEMBL4641777

SMILES CC[C@@H](C)[C@@H](NC(C)C(F)F)C(=O)N1C[C@@](C)(O)C[C@H]1C(=O)NCc1ccc2c(N)nccc2c1

InChI Key InChIKey=OSRSLXKXTGQYBB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50543722   

TargetCoagulation factor XI(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543722(CHEMBL4641777)
Affinity DataIC50: 77nMAssay Description:Inhibition of factor 11a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543722(CHEMBL4641777)
Affinity DataIC50: 798nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543722(CHEMBL4641777)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of factor 12a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543722(CHEMBL4641777)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of factor 7a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543722(CHEMBL4641777)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of factor 9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543722(CHEMBL4641777)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543722(CHEMBL4641777)
Affinity DataIC50: 4.03E+3nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed