BDBM50543574 CHEMBL4639539

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(nc3)-n3cccc3CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=OXHBDBQLFLEDPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543574   

TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543574(CHEMBL4639539)
Affinity DataIC50: 584nMAssay Description:Inhibition of N-terminal GST fused human VEGFR2 cytoplasmic domain (790 to 1356 (end) residues) expressed in baculovirus expression system using FAM-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543574(CHEMBL4639539)
Affinity DataIC50: 114nMAssay Description:Inhibition of N-terminal GST-fused human PDGFRbeta cytoplasmic domain (557 to 1106 (end) residues) expressed in baculovirus expression system using F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed