BDBM50543392 CHEMBL4646866

SMILES Cc1cccc(Nc2nccc(n2)-c2cnn3ncccc23)c1

InChI Key InChIKey=CKXYWSOZFJIUNP-UHFFFAOYSA-N

Data  1 IC50  1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543392   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Sussex

Curated by ChEMBL

LigandBDBM50543392(CHEMBL4646866)Copy SMILESCopy InChI

Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human N-terminal Hex-tagged DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) incubated for 1.5 hrs by ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/13/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Sussex

Curated by ChEMBL

LigandBDBM50543392(CHEMBL4646866)Copy SMILESCopy InChI

Affinity DataKd:  8.90nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant measured for 60 to 300 sec by SPR analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/13/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL