BDBM50543125 CHEMBL4637839

SMILES [H][C@]12CC[C@]([H])(CN(C1)c1cc(C)ns1)[C@H]2Nc1nc2c(O[C@@H](C)C(F)(F)F)cccn2n1

InChI Key InChIKey=CQKFAVNVIQGNST-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543125   

TargetPresenilin-1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50543125(CHEMBL4637839)
Affinity DataIC50: 6nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50543125(CHEMBL4637839)
Affinity DataKd:  85nMAssay Description:Binding affinity to PIK4CB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed