BDBM50542943 CHEMBL4646293

SMILES Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3CC[C@@H](C3)C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1

InChI Key InChIKey=XUVGXIRFSMZJHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542943   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542943(CHEMBL4646293)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542943(CHEMBL4646293)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human C-terminal Ig-Fc-tagged PD1 (Leu25 to Gln167 residues) expressed in HEK293 cells/human C-terminal epitope-His-tagged PDL1 (Phe19 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed