BDBM50542856 CHEMBL4639709

SMILES CC(C)C[C@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=SADYRRFJQXPSEH-UHFFFAOYSA-N

Data  9 KI  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50542856   

TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataEC50:  275nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataEC50:  280nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataEC50:  437nMAssay Description:Agonist activity at human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as intracellular calcium mobilization measured for 43 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataEC50:  440nMAssay Description:Agonist activity at human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as intracellular calcium mobilization measured for 43 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataEC50:  170nMAssay Description:Agonist potency at human Y4 receptor expressed in HEK293T-NlucN-mGSi/Y4R-NlucC cells by miniGsi protein recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO-Gqi5-mtAQE cells measured after 90 mins by MicroBeta plate counter based competi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542856(CHEMBL4639709)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed