BDBM50542606 CHEMBL4636535

SMILES ONC(=O)c1ccc(Oc2ccc(CN3CCCC3c3cccc(F)c3)cc2)c(F)c1

InChI Key InChIKey=PKXVPXZZPYISNC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542606   

TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)
Affinity DataKi:  498nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed