BDBM50542605 CHEMBL4648915

SMILES COc1ccc(cc1)C1CCCN1Cc1ccc(Oc2ccc(cc2)C(=O)NO)cc1

InChI Key InChIKey=DLQCQSHURGAKKI-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50542605   

TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataIC50: 202nMAssay Description:Antagonist activity at human mu opiod receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding incubated for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at human kappa opiod receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human delta opiod receptor expressed in human HEK293 cells assessed as inhibition of DPDPE-induced [35S]GTPgammaS binding incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataKi:  2.31E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed