BDBM50542422 CHEMBL4641929

SMILES Fc1ccc(NC(=O)c2ccc([nH]2)-c2ccc(cc2)C(=O)Nc2ccc(F)cc2)cc1

InChI Key InChIKey=PBJQLWAEYJJWKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542422   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50542422(CHEMBL4641929)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of GST-tagged PTP1B (unknown origin) using pNPP as substrate measured for 3 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50542422(CHEMBL4641929)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed