BDBM50542389 CHEMBL4644195

SMILES CC1(C)OB(OC1(C)C)c1ccc2nc3C(=O)c4cc(F)ccc4-n3c(=O)c2c1

InChI Key InChIKey=NIRSZJKISIXDDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542389   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542389(CHEMBL4644195)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542389(CHEMBL4644195)
Affinity DataIC50: 750nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542389(CHEMBL4644195)
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli BL21 using L-Trp as substrate incubated for 30 mins by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed